Rabeprazole

Rabeprazole is used for:

Treating heartburn or irritation of the esophagus caused by gastroesophageal reflux disease (GERD). It may be used for short-term treatment of ulcers of the small intestine. It may be used with certain antibiotics to treat ulcers of the small intestine and to help prevent them from coming back. It may be used to treat conditions that cause your body to make too much stomach acid (eg, Zollinger-Ellison syndrome). It may also be used for other conditions as determined by your doctor.

Rabeprazole is a proton pump inhibitor. It works by decreasing the amount of acid produced in the stomach.

Use Rabeprazole as directed by your doctor. Check the label on the medicine for exact dosing instructions.

* Take Rabeprazole by mouth with or without food.

* Swallow Rabeprazole whole. Do not break, crush, or chew before swallowing.

* You may take antacids while you are taking Rabeprazole if you are directed to do so by your doctor.

* If you also take an imidazole antifungal (eg, ketoconazole), take it at least 2 hours before taking Rabeprazole .

* If you also take sucralfate, take Rabeprazole at least 30 minutes before taking sucralfate.

* Continue to take Rabeprazole even if you feel well. Do not miss any doses.

* If you miss a dose of Rabeprazole , take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Rabeprazole . * Rabeprazole may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Rabeprazole with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

* Contact your doctor if you have any symptoms of a bleeding ulcer, such as black, tarry stools or vomit that looks like coffee grounds, or if you experience throat pain, chest pain, severe stomach pain, or trouble swallowing.

* Rabeprazole may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Rabeprazole .

* Rabeprazole should be used with extreme caution in Asian patients; the risk of side effects may be increased in these patients.

* Rabeprazole should be used with extreme caution in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.

* PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Rabeprazole while you are pregnant. It is not known if Rabeprazole is found in breast milk. Do not breast-feed while taking Rabeprazole .

Store Rabeprazole at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Rabeprazole out of the reach of children and away from pets.

Quarzan

Clidinium reduces the secretions of certain organs in the body.

Clidinium helps to control conditions such as peptic ulcers that involve excessive stomach acid production.

Clidinium may also be used for purposes other than those listed in this medication guide.

Use caution when driving, operating machinery, or performing other hazardous activities. Clidinium may cause dizziness, drowsiness, or blurred vision. If you experience dizziness, drowsiness, or blurred vision, avoid these activities. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking clidinium.

Avoid becoming overheated in hot weather. Clidinium increases the risk of heat stroke because it causes decreased sweating.

Take clidinium exactly as directed by your doctor. If you do not understand these directions, on ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water.

Clidinium is usually taken three or four times a day with meals and at bedtime. Follow your doctor's instructions.

Store clidinium at room temperature away from moisture and heat.

Many other drugs may increase the side effects of clidinium. Before taking this medication, tell your doctor if you are taking any of the following medicines:

amantadine (Symmetrel)

quinidine (Quinaglute, Cardioquin, Quinora, Quinidex)

antihistamines such as diphenhydramine (Benadryl, many others), brompheniramine (Dimetapp, Bromphen, many others), triprolidine (Actifed, others), and chlorpheniramine (Chlor-Trimeton, others), which are found in many over-the-counter and prescription cough, cold and allergy medications

decongestants and appetite suppressants such as phenylpropanolamine (Dexatrim, others), phenylephrine (Neo-Synephrine, others), and pseudoephedrine (Sudafed, others), which are also found in many over-the-counter and prescription products

phenothiazines such as chlorpromazine (Thorazine) and prochlorperazine (Compazine) other commonly used phenothiazines, including fluphenazine (Prolixin), mesoridazine (Serentil), perphenazine (Trilafon), thioridazine (Mellaril), trifluoperazine (Stelazine), and promazine (Sparine)

tricyclic antidepressants such as amitriptyline (Elavil, Endep), doxepin (Sinequan), and nortriptyline (Pamelor) or

* other commonly used tricyclic antidepressants, including amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), imipramine (Tofranil), protriptyline (Vivactil), and trimipramine (Surmontil).

Clidinium may increase the level of digoxin in your blood. Tell your doctor if you are taking digoxin so that your digoxin levels can be monitored and changes in your dosage can be made if necessary.

Drugs other than those listed here may also interact with clidinium. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Paclitaxel

Paclitaxel must be administered in an appropriate medical setting. Serious allergic reactions, some fatal, have occurred with use of Paclitaxel . DO NOT use Paclitaxel again if you have experienced a severe allergic reaction to it. Stop using Paclitaxel and notify your doctor immediately if you develop signs of an allergic reaction, such as rash; itching; severe dizziness; swelling of hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness. Certain patients with solid tumors or AIDS-related Kaposi sarcoma should not use Paclitaxel . Frequent blood tests should be performed while you are using Paclitaxel because of the risk of bone marrow suppression and serious infection.

Paclitaxel is used for:

Treating ovary and breast cancer. It may be used for other types of cancer as determined by your doctor, which may not be listed in the professional package insert.

Paclitaxel is a chemotherapy medicine. It works by slowing or stopping cancer cells from dividing and growing, so they eventually die.

Use Paclitaxel as directed by your doctor. Check the label on the medicine for exact dosing instructions.

* Paclitaxel may come with an additional patient leaflet. Read it carefully and reread it each time you get Paclitaxel refilled.

* Paclitaxel is usually administered as an injection at your doctor's office, hospital, or clinic. Ask your doctor or pharmacist any questions that you may have about Paclitaxel .

* If nausea, vomiting, diarrhea, or loss of appetite occurs, do not discontinue your medicine. Ask your doctor or pharmacist for ways to lessen these effects.

* Wear gloves while handling Paclitaxel .

* If you get Paclitaxel on your skin, rinse the area thoroughly with soap and water. If you get Paclitaxel in your eyes, nose, or mouth, flush the area thoroughly with water.

* If you miss a dose of Paclitaxel , contact your doctor immediately.

Ask your health care provider any questions you may have about how to use Paclitaxel .

* Serious allergic reactions, some fatal, have occurred with use of Paclitaxel . You will need to take certain other medicines before using Paclitaxel in order to lessen the risk of allergic reaction. Stop using Paclitaxel and notify your doctor immediately if you develop signs of an allergic reaction, such as rash; itching; severe dizziness; swelling of hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness.

* Some patients develop redness or sores in the mouth or on the lips. These symptoms may occur a few days after treatment with Paclitaxel and usually decrease or disappear in 1 week. Talk with your doctor about proper mouth care and other ways to prevent or reduce this side effect.

* Paclitaxel may cause dizziness or vision changes. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Paclitaxel . Using Paclitaxel alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.

* Paclitaxel contains alcohol, which may interact with the effects of other medicines. Alcohol in other beverages or medicines may increase this effect. Before you begin taking any new prescription or over-the-counter medicine, read the ingredients to see if it also contains alcohol. If it does or if you are uncertain, contact your doctor or pharmacist.

* Paclitaxel may lower your body's ability to fight infection. Prevent infection by avoiding contact with people with colds or other infections. Notify your doctor of any signs of infection, including fever, sore throat, rashes, or chills. Also, do not touch your eyes or the inside of your nose unless you have thoroughly washed your hands first.

* Paclitaxel may reduce the number of blood cells that are needed for clotting. Report any unusual bleeding, bruising, blood in the stool, or dark, tarry stools immediately to your doctor.

* If you have not had chickenpox or measles, avoid contact with anyone who has either of these diseases or shingles.

* Check with your doctor before having immunizations (vaccinations).

* Before you have any medical or dental treatments, emergency care, or surgery, tell the doctor or dentist that you are using Paclitaxel .

* LAB TESTS, including blood counts, vital signs (such as pulse and blood pressure), and liver function tests, will be required to monitor your progress and check for side effects. Be sure to keep all doctor and lab appointments.

* Caution is advised when using Paclitaxel in the ELDERLY because they may be more sensitive to the effects of Paclitaxel , especially effects on the bone marrow (myelosuppression).

* Paclitaxel is not recommended for use in CHILDREN. Safety and effectiveness in this age group have not been confirmed.

* Women of childbearing age should use an effective form of birth control (eg, condoms) while using Paclitaxel .

* PREGNANCY AND BREAST-FEEDING: Paclitaxel has been shown to cause harm to the fetus. If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Paclitaxel during pregnancy. It is unknown if Paclitaxel is excreted in breast milk. Do not breast-feed while using Paclitaxel .

Store Paclitaxel as directed on the prescription label. Keep Paclitaxel out of the reach of children and away from pets.

Ocuclear

OcuClear Drops is used for:

Relieving redness in the eye caused by minor irritation.

OcuClear Drops is a decongestant used in the eye. It works by narrowing the blood vessels in the eye, which helps you by relieving irritation.

Use OcuClear Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

* If you wear contact lenses, remove them before using OcuClear Drops.

* To use OcuClear Drops, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye and continue to apply pressure for 1 to 2 minutes after using the medicine. Do not blink. Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them. To prevent germs from entering your medicine, do not touch the applicator tip to any surface, including your eye. Keep the container tightly closed.

* If you miss a dose of OcuClear Drops and are using it regularly, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use OcuClear Drops.

* Do not exceed the recommended dose or use OcuClear Drops for longer than 3 days without checking with your doctor. If your symptoms do not improve within 3 days or if they become worse, check with your doctor.

* OcuClear Drops is not recommended for use in CHILDREN younger than 6 years of age. Safety and effectiveness in this age group have not been confirmed.

* PREGNANCY AND BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using OcuClear Drops during pregnancy. It is unknown if OcuClear Drops is excreted in breast milk. If you are or will be breast-feeding while you are using OcuClear Drops, check with your doctor or pharmacist to discuss the risks to your baby.

Store OcuClear Drops at room temperature, between 68 and 77 degrees F (20 and 25 degrees C) in a tightly closed container. Store away from heat and light. Keep OcuClear Drops out of the reach of children and away from pets.

Nabumetone

Nabumetone is a nonsteroidal anti-inflammatory drug (NSAID). It may cause an increased risk of serious and sometimes fatal heart and blood vessel problems (eg, heart attack, stroke). The risk may be greater if you already have heart problems or if you take Nabumetone for a long time. Do not use Nabumetone right before or after bypass heart surgery.

Nabumetone may cause an increased risk of serious and sometimes fatal stomach ulcers and bleeding. Elderly patients may be at greater risk. This may occur without warning signs.

                       Nabumetone is used for:

Treating rheumatoid arthritis or osteoarthritis. It may also be used for other conditions as determined by your doctor.

Nabumetone is an NSAID. Exactly how it works is not known. It may block certain substances in the body that are linked to inflammation. NSAIDs treat the symptoms of pain and inflammation. They do not treat the disease that causes those symptoms.

                        Use Nabumetone as directed by your doctor. Check the label on the medicine for exact dosing instructions.

    * Nabumetone comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Nabumetone refilled.

    * Take Nabumetone by mouth. It may be taken with food if it upsets your stomach. This may not lower the risk of stomach or bowel problems (eg, bleeding, ulcers). Talk with your doctor if you have persistent stomach upset.

    * Take Nabumetone with a full glass of water (8 oz/240 mL) as directed by your doctor.

    * If you miss a dose of Nabumetone and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Nabumetone

                        .    * Nabumetone may cause dizziness or drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Nabumetone with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

    * Serious stomach ulcers or bleeding can occur with the use of Nabumetone . Taking it in high doses or for a long time, smoking, or drinking alcohol increases the risk of these side effects. Taking Nabumetone with food will NOT reduce the risk of these effects. Contact your doctor or emergency room at once if you develop severe stomach or back pain; black, tarry stools; vomit that looks like blood or coffee grounds; or unusual weight gain or swelling.

    * Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.

    * Nabumetone is an NSAID. Before you start taking any new medicine, read the ingredients. If it also has an NSAID (eg, ibuprofen) in it, check with your doctor. If you are not sure, check with your doctor or pharmacist.

    * Do not take aspirin while you are using Nabumetone unless your doctor tells you to.

    * Nabumetone may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Nabumetone . Use a sunscreen or wear protective clothing if you must be outside for any length of time.

    * Lab tests, including kidney function, complete blood cell counts, and blood pressure, may be done to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.

    * Use Nabumetone with caution in the ELDERLY; they may be more sensitive to its effects, including stomach bleeding and kidney problems.

    * Nabumetone should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.

    * PREGNANCY and BREAST-FEEDING: Nabumetone may harm the fetus. Do not use it during the last 3 months of pregnancy. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Nabumetone while you are pregnant. It is not known if Nabumetone is found in breast milk. Do not breast-feed while you are taking Nabumetone .

                                Store Nabumetone at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Nabumetone out of the reach of children and away from pets.